Many hospitals and laboratories activities can only take place within a clean room such like as Tissue processing , banking facilities, radiations and image processing. These clean rooms must meet regulatory requirements and international standards.

The study of microorganisms, whether in a medical, molecular or other specialty or context requires highly controlled environments. To meet these requirements, most microbiology cleanrooms adhere to an ISO Class 7 to ISO Class 5 standard, along with a minimum of ISO Class 5 biological safety hood as the primary engineering control.